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Elestrin demonstrated significant reduction in the frequency and severity of hot flashes.

Patients were experiencing an average of 13 hot flashes a day with a mean severity score of 2.4 on a 4-point scale, where 3.0 = severe.1,2

Frequency Reduction

Elestrin significantly reduced the mean number of hot flashes by week 3 using the 2-pump dose, and by week 5 using 1-pump.1,2

Severity Reaction

Elestrin significantly reduced the average severity of hot flashes by week 4 using the 2-pump dose, and by week 5 using the 1-pump dose.1,2

Flexible dosing titrates up or down easily, economically.

Elestrin’s 1-pump dose delivers 0.87 g/d of estradiol, and 1.7 g/d of estradiol using the 2-pump dose.

Patients may be titrated up or down, depending on severity and frequency of hot flashes, without requiring a new prescription or co-payment by the patient.

References:

1. Simon JA, Bouchard C, Waldbaum A, et al. Low dose of transdermal estradiol gel for treatment of symptomatic postmenopausal women: a randomized controlled trial. Obstet Gynecol. 2007.

2. Elestrin™ [package insert]. San Antonio TX: Kenwood Therapeutics, 2007.

 

Important Safety InformationElestrin is indicated for the treatment of moderate-to-severe vasomotor symptoms associated with menopause.

Estrogens, with or without progestins, should not be used for the prevention of cardiovascular disease or dementia. Estrogen and progestin therapy has shown an increased risk of breast cancer, heart attack, and blood clots. Estrogen therapy, with or without progestins, increases the risk of stroke and dementia. Estrogen therapy alone increases the risk of endometrial cancer. The most frequently reported adverse events in clinical trials were nasopharyngitis, breast tenderness, upper respiratory tract infection, and metrorrhagia.

Please see Full Prescribing Information, including Black Box Warning

 
 

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A Survey of 300 untreated menopausal women reveal what they want from the application of transdermal estrogen therapy†:

"I want a product I can apply and forget it."

"I’d rather just rub the product in and forget it’s there."

"For me, it’s easier to get into a daily habit."

"I like the control of applying [it] right on my upper arm."

"Make it clear and easy to apply."

†A blinded survey of 300 women with hot flashes to evaluate the importance of various attributes of transdermal estrogen therapy and the preference for various topical estrogen therapy products. Azur Pharma; 2009.